Thursday, May 24, 2007

Nature on Epigenetics

From http://www.nature.com/nature/journal/v447/n7143/full/447395a.html:
"Epigenetics is typically defined as the study of heritable changes in gene expression that are not due to changes in DNA sequence. Diverse biological properties can be affected by epigenetic mechanisms: for example, the morphology of flowers and eye colour in fruitflies.
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In this Insight, we take a wide view of the epigenetics field, highlighting current topics of interest — from the influence of chromatin and chromosome organization on gene expression to the roles of epigenetic mechanisms in development and disease. And under this broad umbrella, the very definition of epigenetics is scrutinized. We hope that you enjoy these exciting reviews and thank the authors for their contributions."
At the top right of the page clicking on 'next' takes to the next article. All articles are downloadable now. List of articles:

Perceptions of epigenetics p396
Adrian Bird

Transcription and RNA interference in the formation of heterochromatin p399
Shiv I. S. Grewal & Sarah C. R. Elgin

The complex language of chromatin regulation during transcription p407
Shelley L. Berger

Nuclear organization of the genome and the potential for gene regulation p413
Peter Fraser & Wendy Bickmore

Epigenetic inheritance in plants p418
Ian R. Henderson & Steven E. Jacobsen

Stability and flexibility of epigenetic gene regulation in mammalian development p425
Wolf Reik

Phenotypic plasticity and the epigenetics of human disease p433
Andrew P. Feinberg

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